重组小鼠IL-13

产品货号：

GS4560

中文名称：

重组小鼠IL-13

英文名称：

Recombinant Murine Interleukin-13

产品规格：

2μg

发货周期：

1～3天

产品价格：

询价

分子量：Approximately 12.3kDa,a single non-glycosylated polypeptide chain containing 111 amino acids.
储存条件：冷冻（-20℃）

概述

Murine Interleukin-13(IL-13)is expressed by the IL13 gene located on the chromosome 11 and secreted by many cell types,especially T helper type 2(Th2)cells.Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites.IL-13 has been implicated as a key factor in asthma,allergy,atopy and inflammatory response,establishing the protein as a valuable therapeutic target.Human,mouse and rat IL-3 share low homology,but have cross species activity.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 4ng/ml,corresponding to a specific activity of>2.5×105 IU/mg.
成分	Lyophilized from a 0.2μmfiltered solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rMuIL-13 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F

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